Sesame oil consumption exerts a beneficial effect on endothelial function in hypertensive men.


Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics, Harokopio University, Athens, Greece.


Background: The aim of the study was to investigate the effects of sesame oil on endothelial function and to detect the underlying mechanisms, both in the postprandial state and after long-term consumption.Design: We enrolled 30 hypertensive men in a two-phase study. In the first phase, 26 volunteers consumed 35 g of either sesame oil or control oil. Endothelial function, inflammatory activation and nitric oxide syntase (NOS) inhibition was assessed after a 12-hour fast and 2 hours after consumption of an oil-containing standardized meal. In the second phase, 30 volunteers consumed 35 g of sesame oil or control oil daily for 2 months and the above-mentioned parameters were assessed at baseline, 15, 30 and 60 days.Methods: Endothelial function was estimated by endothelium-dependent FMD (flow-mediated dilatation) of the brachial artery.Results: Flow-mediated dilatation (FMD) improved significantly both after acute (p = 0.001) and long-term sesame oil consumption (p = 0.015, p = 0.005 and p = 0.011 for 15, 30 and 60 days respectively). Intracellular adhesion molecule (ICAM) levels decreased significantly after only 60 days of daily sesame oil intake (p = 0.014). By contrast, no changes were observed in the control group in either phase of the study.Conclusions: This is the first study to show that sesame oil consumption exerts a beneficial effect on endothelial function and this effect is sustained with long-term daily use.


Potential of herbs in skin protection from ultraviolet radiation.


Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University in Belgrade, Vojvode Stepe Belgrade, Serbia.


Herbs have been used in medicines and cosmetics from centuries. Their potential to treat different skin diseases, to adorn and improve the skin appearance is well-known. As ultraviolet (UV) radiation can cause sunburns, wrinkles, lower immunity against infections, premature aging, and cancer, there is permanent need for protection from UV radiation and prevention from their side effects. Herbs and herbal preparations have a high potential due to their antioxidant activity, primarily. Antioxidants such as vitamins (vitamin C, vitamin E), flavonoids, and phenolic acids play the main role in fighting against free radical species that are the main cause of numerous negative skin changes. Although isolated plant compounds have a high potential in protection of the skin, whole herbs extracts showed better potential due to their complex composition. Many studies showed that green and black tea (polyphenols) ameliorate adverse skin reactions following UV exposure. The gel from aloe is believed to stimulate skin and assist in new cell growth. Spectrophotometer testing indicates that as a concentrated extract of Krameria triandra it absorbs 25 to 30% of the amount of UV radiation typically absorbed by octyl methoxycinnamate. Sesame oil resists 30% of UV rays, while coconut, peanut, olive, and cottonseed oils block out about 20%. A "sclerojuglonic" compound which is forming from naphthoquinone and keratin is the reaction product that provides UV protection. Traditional use of plant in medication or beautification is the basis for researches and making new trends in cosmetics. This review covers all essential aspects of potential of herbs as radioprotective agents and its future prospects.



Our aim is to highlight scientific research in natural substances, which have shown great promise in vitro and in vivo.

After powerful scientific evidence has shown the efficacy of natural substances, many researchers have recommended clinical trials should commence because the results have shown such great potential. We are still waiting for these clinical trials to begin, but as clinical trials are very expensive, and natural substances are low cost and cannot be patented, there is little or no funding available for such trials. 

As little progress has been made in finding a "cure" for cancer, there is increasing interest in natural cancer remedies, Therefore, we are publishing links to some of this research, so that patients and caregivers have validated scientific evidence to help them make informed decisions about their treatment options.

For guidance on treatment with natural remedies and substances, we would always recommend the support of a naturopathic or integretive medicinal practice.

Useful Links:

US National Library of MedicineNational Institutes of Health: http://www.ncbi.nlm.nih.gov/pubmed/

Link to directory of naturopathic doctors: http://www.naturopathic.org/AF_MemberDirectory.asp?version=2

Integrative Medicine: https://www.integrativepractitioner.com/

GreenMedInfo Research & News: http://www.greenmedinfo.com/

BioMed Central Research: http://www.biomedcentral.com/

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